![]() ![]() Goldenseal and blood clotting medications.John’s Wort can reduce the effectiveness of these medications, and mixing them can cause harmful effects. ![]() John’s Wort supplements can interact with many medications, including antidepressants, birth control pills, and blood thinners. If you are taking a blood thinner, ask your provider before you start taking vitamin E. Vitamin E can increase the risk of bleeding when it’s taken with blood-thinning medications like warfarin.
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